Elisabeth Eckert
PD Dr. Elisabeth Eckert
Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin
Lehrstuhl für Arbeits- und Sozialmedizin
Henkestr. 9-11
91054 Erlangen
- Telefon: +49 9131 85-26127
- Faxnummer: +49 9131 85-22317
- E-Mail: elisabeth.eckert@fau.de
- Webseite: https://www.ipasum.med.fau.de/
Sprechzeiten
nur MontagE-Mail: DFG-AibM@fau.de
Dissertation an der FAU Erlangen-Nürnberg
2024
- Eckert, E., Jäger, T., Hiller, J., Leibold, E., Bader, M., & Göen, T. (2024). Biotransformation and toxicokinetics of 2-phenoxyethanol after oral exposure in humans: a volunteer study. Archives of Toxicology. https://doi.org/10.1007/s00204-024-03717-2
- Jäger, T., Eckert, E., Leibold, E., & Bader, M. (2024). A specific and sensitive GC-MS-MS method for the quantitative determination of 2-phenoxyethanol and selected metabolites in human blood and urine. Journal of Analytical Toxicology, 48(6), 419-428. https://doi.org/10.1093/jat/bkae037
2023
- Eckert, E., Kuhlmann, L., Göen, T., & Münch, F. (2023). Assessment of the plasticizer exposure of hospital workers regularly handling medical devices: A pilot study. Environmental Research, 237. https://doi.org/10.1016/j.envres.2023.117028
2022
- Jager, T., Eckert, E., Leibold, E., & Bader, M. (2022). Reliable determination of the main metabolites of 2-phenoxyethanol in human blood and urine using LC-MS/MS analysis. Analytical Methods. https://doi.org/10.1039/d2ay01407f
- Kuhlmann, L., Muench, F., Göen, T., & Eckert, E. (2022). Simultaneous and sensitive determination of the main metabolites of the plasticizer DEHP and its substitutes DEHTP, DINCH and TEHTM in human urine by coupling of on-line SPE, UHPLC and tandem mass spectrometry. Analytical Methods. https://doi.org/10.1039/d2ay01293f
2021
- Kuhlmann, L., Göen, T., & Eckert, E. (2021). Sensitive monitoring of the main metabolites of tri-(2-ethylhexyl) trimellitate (TOTM) in urine by coupling of on-line SPE, UHPLC and tandem mass spectrometry. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 1171. https://doi.org/10.1016/j.jchromb.2021.122618
- Murawski, A., Schmied-Tobies, M.I., Rucic, E., Schmidtkunz, C., Küpper, K., Leng, G.,... Kolossa-Gehring, M. (2021). Metabolites of 4-methylbenzylidene camphor (4-MBC), butylated hydroxytoluene (BHT), and tris(2-ethylhexyl) trimellitate (TOTM) in urine of children and adolescents in Germany – human biomonitoring results of the German Environmental Survey GerES V (2014–2017). Environmental Research, 192. https://doi.org/10.1016/j.envres.2020.110345
2020
- Eckert, E., Müller, J., Höllerer, C., Purbojo, A., Cesnjevar, R., Göen, T., & Münch, F. (2020). Plasticizer exposure of infants during cardiac surgery. Toxicology Letters, 330, 7-13. https://doi.org/10.1016/j.toxlet.2020.04.004
- Kaestner, F., Seiler, F., Rapp, D., Eckert, E., Müller, J., Metz, C.,... Göen, T. (2020). Exposure of patients to di(2-ethylhexy)phthalate (DEHP) and its metabolite MEHP during extracorporeal membrane oxygenation (ECMO) therapy. PLoS ONE, 15(1), e0224931-. https://doi.org/10.1371/journal.pone.0224931
- Weistenhöfer, W., Eckert, E., Schäferhenrich, A., Göen, T., Drexler, H., & Hartwig, A. (2020). Antimon-Biomonitoring – Ein Beispiel für die kohärente Arbeitsweise der Arbeitsgruppen der Ständigen Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe. In Proceedings of the 60. Jahrestagung der DGAUM 2020. München, DE.
2018
- Höllerer, C., Becker, G., Göen, T., & Eckert, E. (2018). Human metabolism and kinetics of tri-(2-ethylhexyl) trimellitate (TEHTM) after oral administration. Archives of Toxicology, 92(9), 2793-2807. https://doi.org/10.1007/s00204-018-2264-2
- Höllerer, C., Becker, G., Göen, T., & Eckert, E. (2018). Regioselective ester cleavage of di-(2-ethylhexyl) trimellitates by porcine liver esterase. Toxicology in Vitro, 47, 178-185. https://doi.org/10.1016/j.tiv.2017.11.015
- Höllerer, C., Göen, T., & Eckert, E. (2018). Comprehensive monitoring of specific metabolites of tri-(2-ethylhexyl) trimellitate (TEHTM) in urine by column-switching liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry, 410(18), 4343-4357. https://doi.org/10.1007/s00216-018-1086-7
- Münch, F., Höllerer, C., Klapproth, A., Eckert, E., Rueffer, A., Cesnjevar, R., & Göen, T. (2018). Effect of phospholipid coating on the migration of plasticizers from PVC tubes. Chemosphere, 202, 742-749. https://doi.org/10.1016/j.chemosphere.2018.03.136
- Seitz, M., Kilo, S., Eckert, E., Mueller, J., Drexler, H., & Göen, T. (2018). Validity of different biomonitoring parameters for the assessment of occupational exposure to N,N-dimethylformamide (DMF). Archives of Toxicology, 92(7), 2183-2193. https://doi.org/10.1007/s00204-018-2219-7
2017
- Höllerer, C., Mueller, J., Göen, T., & Eckert, E. (2017). Isomeric separation and quantitation of di-(2-ethylhexyl) trimellitates and mono-(2-ethylhexyl) trimellitates in blood by LC-MS/MS. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 1061-1062, 153-162. https://doi.org/10.1016/j.jchromb.2017.07.014
2016
- Eckert, E., Münch, F., Göen, T., Purbojo, A., Mueller, J., & Cesnjevar, R. (2016). Comparative study on the migration of di-2-ethylhexyl phthalate (DEHP) and tri-2-ethylhexyl trimellitate (TOTM) into blood from PVC tubing material of a heart-lung machine. Chemosphere, 145, 10-6. https://doi.org/10.1016/j.chemosphere.2015.11.067
- Göen, T., Von Helden, F., Eckert, E., Knecht, U., Drexler, H., & Walter, D. (2016). Metabolism and toxicokinetics of 1,4-dioxane in humans after inhalational exposure at rest and under physical stress. Archives of Toxicology, 90(6), 1315-24. https://doi.org/10.1007/s00204-015-1567-9
- Kilo, S., Hofmann, B., Eckert, E., Göen, T., & Drexler, H. (2016). Evaluation of biomarkers assessing regular alcohol consumption in an occupational setting. International Archives of Occupational and Environmental Health, 89(8), 1193-1203. https://doi.org/10.1007/s00420-016-1155-1
2015
- Eckert, E., Müller, J., & Göen, T. (2015). Simultaneous determination of polyvinylchloride plasticizers di(2-ethylhexyl) phthalate and tri(2-ethylhexyl) trimellitate and its degradation products in blood by liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1410, 173-80. https://doi.org/10.1016/j.chroma.2015.07.083
2014
- Eckert, E., & Göen, T. (2014). Rapid determination of four short-chain alkyl mercapturic acids in human urine by column-switching liquid chromatography-tandem mass spectrometry. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 965, 54-60. https://doi.org/10.1016/j.jchromb.2014.06.009
2013
- Peukert, W., Tietze, R., Lyer, S., Dürr, S., Struffert, T., Engelhorn, T.,... Alexiou, C. (2013). Efficient drug-delivery using magnetic nanoparticles--biodistribution and therapeutic effects in tumour bearing rabbits. Nanomedicine : nanotechnology, biology, and medicine, 9(7), 961-971. https://doi.org/10.1016/j.nano.2013.05.001
Eckert E., Göen Th. (2014): Rapid determination of four short-chain alkyl mercapturic acids in human urine by column-switching liquid chromatography-tandem mass spectrometry. J. Chromatogr. B, 965, 54-60. [Link]
Eckert E., W. Gries, Th. Göen, G. Leng (2013): Reliable quantitation of β-hydroxyethoxyacetic acid in human urine by an isotope-dilution GC-MS procedure. J. Chromatogr. B, 935, 80-84. [Link]
R. Tietze, S. Lyer, S. Dürr, T. Struffert, T. Engelhorn, M. Schwarz, E. Eckert, Th. Göen, S. Vasylyev, W. Peukert, F. Wiekhorst, L. Trahms, A. Dörfler, C. Alexiou (2013): Efficient drug-delivery using magnetic nanoparticles – biodistribution and therapeutic effects in tumour bearing rabbits. Nanomedicine: Nanotechnology, Biology, and Medicine, 9, 961-971. [Link]
Eckert E., Leng G., Gries W., Göen Th. (2013): Excretion of mercapturic acids in human urine after occupational exposure to 2-chloroprene. Arch. Toxicol., 87, 1095-1102. [Link]
Eckert E., Leng G., Gries W., Göen Th. (2012): A method for the simultaneous determination of mercapturic acids as biomarkers of exposure to 2-chloroprene and epichlorohydrin in human urine. J. Chromatogr. B, 889-890, 69-76. [Link]
Göen Th., Eckert E., Schäferhenrich A., Hartwig A. (2012): Allocation of reliable analytical procedures for human biomonitoring by the DFG Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. Int. J. Hyg. Environ. Health, 215, 233-237. [Link]
Eckert, E., Schmid, K., Schaller, B., Hiddemann-Koca, K., Drexler, H., Göen, T. Mercapturic acids as metabolites of alkylating substances in urine samples of German inhabitants (2011) International Journal of Hygiene and Environmental Health. [Link]
Eckert, E., Drexler, H., Göen, T. Determination of six hydroxyalkyl mercapturic acids in human urine using hydrophilic interaction liquid chromatography with tandem mass spectrometry (HILIC-ESI-MS/MS) (2010) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 878 (27), pp. 2506-2514. [Link]
Elisabeth Eckert, Gabriela Ratz, Hans Drexler, Thomas Göen (2010). LC-MS/MS-Verfahren für das Biomonitoring von Belastungen mit dem Pflanzenschutzmittel Clothianidin. Dokumentation der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V., S. 657-659, Eigenverlag, Aachen.
Elisabeth Eckert, Thomas Göen, Hans Drexler (2009). Bestimmung von Hydroxyalkylmerkaptursäuren im Urin mittels einer LC-MS/MS-Multi-Methode zum Biomonitoring von kanzerogenen Arbeitsstoffen. Dokumentation der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V., S. 151-156, Eigenverlag, Aachen.
T. Göen, E. Eckert, S. Kilo, H. Drexler: Suitability of N,N-dimethylformamide derived hemoglobin adduct as long-term biomarker. International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM 2013), 09.-11. September 2013 in Manchester, UK.
Göen Th., Kilo S., Eckert E., Straube S., Seitz M., Hofmann B., Battermann O., Drexler H.; Assoziationen zwischen der DMF-Luftbelastung und verschiedenen DMF-Biomonitoringparametern. 53. Jahrestagung der Deutschen Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM), 13.-16. März 2013 in Bregenz, Österreich.
Göen Th., Eckert E., Schäferhenrich A., Hartwig A.; Reliable methods for biomonitoring of occupational exposure published by the DFG commission for the investigation of health hazards of chemical compounds in the work area; 30th International Congress on Occupational Health (ICOH) 18.-23. März 2012 in Cancún, Mexiko
Eckert E., Gries W., Leng G., Göen Th.;Biomonitoring bei beruflicher 2-Chloropren-Belastung; Deutsche Gesellschaft für Arbeitsmedizin und Umweltmedizin e.V. (DGAUM) 52. Wissenschaftliche Jahrestagung 14.-17. März 2012 in Göttingen [Poster]
Eckert E., Gries W., Göen Th., Leng G.; 77. Jahrestagung der Deutschen Gesellschaft für Experimentelle und Klinische Pharmakologie und Toxikologie e. V. (DGPT) (30.03.-01.04.2011) Nachweis von S-(3,4-Dihydroxybutyl)merkaptursäure als Hauptmetaboliten des 2-Chloropren im Menschen.
Göen Th., Eckert E., Schäferhenrich A., Hartwig A.; International conference on „Human Biomonitoring – Interest to Policymakers, Challenge for Science –” Berlin (26.-28.09.2010) Allocation of reliable analytical procedures for human biomonitoring by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area of the DFG.
Eckert E., Drexler H., Göen Th.; 8. International Symposium on Biological Monitoring in Occupational and Environmental Health (ISBM 2010), Espoo, Finland (06.-08.09.2010) Determination of six hydroxyalkyl mercapturic acids in human urine of the general population by HILIC-MS/MS.
Eckert E., Ratz G., Drexler H., Göen Th.; 50. Jahrestagung der DGAUM e.V., Dortmund (16.-18.06.2010) LC-MS/MS-Verfahren für das Biomonitoring von Belastungen mit dem Pflanzenschutzmittel Clothianidin.